Potential function
Cell dynamics are ruled by physical interactions determined by a two dimensional potential function which accounts physical stress and binding forces.
Cancer Invasion
Cancer invasion of tissue is the hallmark of metastasis. It can be considered as a multistep process where degradation of the adjacent stroma and interaction with growth factors can alter the tumour interface and produce invasive fingers. We use a hybrid PDE-Individual based approach to study the interactions between cancer cells, the ECM and the matrix degradative enzymes .
Publications:
Mathematical Modelling of Cancer Cell Invasion of Tissue.
Ignacio Ramis-Conde, Mark A.J. Chaplain, Alexander R.A. Anderson. Math. and Comp. Mod.
Enzyme production 1
Enzyme production 2
Enzyme production 3
